Publications | ERBC

Fares R, Champeroux P et al, 2023. Simultaneous assessment of central nervous and respiratory systems using jacketed telemetry in socially-housed rats: Application of the “3Rs” principles in core battery safety pharmacology studies Journal of Pharmacological and Toxicological Methods
Champeroux P, Fares R, Bastogne T, Richard S, Le Guennec JY, Thireau J et al, 2022. Contribution of haemodynamic side effects and associated autonomic reflexes to ventricular arrhythmias triggering by torsadogenic hERG blocking drugs British Journal of Pharmacology
Fares R, Flénet T, Vial J, Roger V, Bory C, Baudet S et al, 2022. Non invasive jacketed telemetry in socially-housed rats for a combined assessment of respiratory system, electrocardiogram and activity using the DECRO system Journal of Pharmacological and Toxicological Methods
Maleysson V, Page G, Janet T, Klein RL, Haida O, Maurin A, Richard S, Champeroux P, Fauconneau B et al, 2019. Relevance of electroencephalogram assessment in amyloid and tau pathology in rat.
Fiascarelli A, Bigioni M, Bressan A, Carrisi C, Bellarosa D, Salerno M, Bugianesi R, Manno RA, Morales CB, Arribas J, Dusek RL, Pham PH, Dee Aud RA, Trang M, Terrett J, Wilson KE, Rohlff C, Manzini S, Pellacani A, Binaschi M et al, 2019. MEN1309/OBT076, a first-in-class Antibody-drug Conjugate (ADC) targeting CD205 in solid tumors.
Mosesso P, Piane M, Pepe G, Cinelli S, Chessa L et al, 2018. Modulation of hypersensitivity to oxidative DNA damage in ATM defective cells induced by potassium bromate by inhibition of the Poly (ADP-ribose) polymerase (PARP).
Champeroux P, Fesler P, Jude S, Richard S, Le Guennec JY, Thireau J et al, 2018. High-frequency autonomic modulation: a new model for analysis of autonomic cardiac control.
Ramot Y, Nyska A, Adar L, Durlach C, Fishelovitch D, Sacco G, Manno RA, Sacco G, Oren S, Perlstein I, Yacobi-Zeevi O et al, 2018. ND0701, A Novel Formulation of Apomorphine for Subcutaneous Infusion, in Comparison to a Commercial Apomorphine Formulation: 28-Day Pharmacokinetic Study in Minipigs and a Phase I Study in Healthy Volunteers to Assess the Safety, Tolerability, Pharmacokin
Le Guennec JY, Thireau J, Ouillé A, Roussel J, Roy J, Richard S, Richard S, Martel E, Champeroux P et al, 2017. Inter-individual variability and modeling of electrical activity: a possible new approach to explore cardiac safety? Scientific Reports
Le Guennec JY, Thireau J, Ouillé A, Roussel J, Roy J, Richard S, Martel E, Champeroux P et al, 2016. Inter-individual variability and modeling of electrical activity: a possible new approach to explore cardiac safety?
Chicco D, Orlandi F, Venturella S, Di Manno P et al, 2016. Safety assessment of a formulation for 68Ga-DOTATOC (68Ga-edotreotide or 68Ga-DOTA0-Tyr3-octreotide) preparation: Case studies in rats and rabbits
Manno RA, Grassetti A, Oberto G, Nyska A, Ramot Y et al, 2016. The minipig as a new model for the evaluation of doxorubicin-induced chronic toxicity.
Harrill JA, Layko D, Nyska A, Hukkanen RR, Manno RA, Grassetti A, Lawson M, Martin G, Budinsky RA, Rowlands JC, Thomas RS et al, 2016. Aryl hydrocarbon receptor knockout rats are insensitive to the pathological effects of repeated oral exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Weaver ML, Grossi AB, Schützsack J , Parish J, Løgsted J, Bøgh IB, Cameron D, Harvey W, Festag M , Downes N , Venturella S, Schlichtiger J, Mhedhbi S, Ross V, Kissner T, Stark C, Milano S, Heining P, Sanchez-Felix M et al, 2016. Vehicle Systems and Excipients Used in Minipig Drug Development Studies.
Champeroux P, Le Guennec JY, Jude S, Laigot-Barbé C, Maurin A, Sola ML, Fowler JS, Richard S, Thireau J et al, 2016. The high frequency relationship: implications for torsadogenic hERG blockers